Developing a Robust Manufacturing Process for Integrated Circuit T Cell (ICT) Products, Using Targeted, Crispr Integration of Transgenes by Electroporation (CITE) Editing
Time: 11:40 am
day: Day Two AM
Details:
• Tackling solid tumors by combining logic gated targeting and reprogramming of T cells to increase specificity, potency, and persistence
• Developing a non-viral gene editing approach to precisely insert a large transgene for a homogenous cell product
• Delivering a robust manufacturing process that can achieve high therapeutic yields while maintaining favorable memory phenotype