Jacob Okhovat
Associate Director, Process Development AstraZeneca
Jacob Okhovat, is Associate Director of Process Development, Cell Therapy Development & Operations at AstraZeneca, where he leads process design, optimization, and scale-up activities for advanced cell therapy modalities. With over 15 years of experience in bioprocessing and clinical manufacturing, Jacob has driven robust strategies across upstream and downstream development to support translational impact. His background spans roles from senior scientist to leadership, enabling the delivery of reliable, scalable manufacturing solutions for innovative cell-based therapies advancing through the clinical pipeline.
Seminars
Thursday 16th July 2026
Optimizing Early-Stage Autologous Cell Therapy Processes to Enable Future Commercial Scale-Out & Manufacturing Feasibility
3:45 pm
- Implementing early-stage process optimization strategies across cost, manufacturing complexity, and regulatory considerations to establish foundations for commercial viability
- Addressing critical decisions during early development that impact future scale-out capabilities, from producing 10 doses in phase one to thousands in commercial manufacturing
- Balancing multiple optimization workstreams, including out-of-spec reduction and process simplification during early phases to prevent costly late-stage manufacturing bottlenecks
